Alkyl Polyglycosides mu Zosamalira Munthu

Pazaka khumi zapitazi, kupanga zinthu zopangira zinthu zosamalira munthu kwapita patsogolo m'magawo atatu:

(1) kufatsa ndi kusamalira khungu

(2) Miyezo yapamwamba kwambiri pakuchepetsa zopangira ndikutsata zonyansa

(3) kuyanjana kwachilengedwe.

Malamulo ovomerezeka ndi zosowa za ogula akuchulukirachulukira kulimbikitsa chitukuko chatsopano chomwe chimatsatira mfundo za ndondomeko ndi kukhazikika kwa mankhwala. Mbali imodzi ya mfundoyi ndi kupanga alkyl glycosides kuchokera kumafuta a masamba ndi chakudya kuchokera ku gwero longowonjezwdwa. Kupititsa patsogolo ukadaulo wamalonda kumafuna kuwongolera kwakukulu pazinthu zopangira, machitidwe ndi kukonza zinthu kuti zikwaniritse zofunikira zazinthu zamakono zodzikongoletsera ndikuzipanga pamtengo wokwanira. M'munda wa zodzoladzola, alkyl glucoside ndi mtundu watsopano wa surfactant wokhala ndi zinthu wamba zomwe si-ionic ndi anionic. Mpaka pano, gawo lalikulu kwambiri lazamalonda ndi oyeretsa omwe amaimiridwa ndi C8-14 alkyl glycosides, omwe amadziwika ndi maonekedwe awo a khungu ndi tsitsi. C12-14 alkyl polyglycoside imagwira ntchito ngati emulsifier m'mapangidwe enieni komanso makamaka mu ma microemulsions ndikuphunzira momwe C16-18 alkyl polyglycoside imagwirira ntchito ngati maziko odzipangira okha o / w ophatikizidwa ndi mowa wamafuta.

Pakupanga kuyeretsa thupi, chowonjezera chatsopano chamakono chiyenera kugwirizana bwino ndi khungu ndi mucous nembanemba. Dermatological ndi toxicological mayesero m`pofunika kuwunika chiopsezo latsopano surfactant ndi kamangidwe chofunika kwambiri kuzindikira zotheka kukondoweza kwa maselo amoyo mu epidermal woyambira wosanjikiza. M'mbuyomu, izi zakhala maziko a zonena za kufatsa kwapang'onopang'ono. Panthawi imodzimodziyo, tanthawuzo la kufatsa lasintha kwambiri.Lero, kufatsa kumamveka ngati kugwirizanitsa kwathunthu kwa surfactants ndi physiology ndi ntchito ya khungu la munthu.

Kupyolera mu njira zosiyanasiyana za dermatological ndi biophysical, zotsatira za thupi za surfactants pakhungu zinaphunziridwa, kuyambira pamwamba pa khungu ndikupita kumalo ozama a maselo oyambira kupyolera mu stratum corneum ndi ntchito yake yotchinga.

Ma Alkyl polyglycosides okhala ndi C8 mpaka C16 alkyl chain ali m'gulu la ofatsa kwambiri opangidwa ndi ma surfactants oyeretsa thupi. Mu kafukufuku watsatanetsatane, kuyanjana kwa alkyl polyglycosides kunafotokozedwa ngati ntchito ya unyolo wa alkyl woyera ndi digiri ya polymerization. Izi zikufanana ndi kuwunika ndi magulu ena a surfactants. Kuphatikiza apo, kupsa mtima kumachepa pang'ono ndi kuchuluka kwa polymerization (kuchokera ku DP = 1.2 mpaka DP = 1.65).

Zogulitsa za APG zokhala ndi utali wosakanikirana wa alkyl utali zimayenderana bwino kwambiri ndi gawo lalitali la alkili glycosides (C12-14). Zinafaniziridwa ndi kuwonjezeredwa kwa alkyl ether sulphates ofatsa kwambiri, amphoteric glycine kapena amphoteric acetate, ndi mapuloteni ocheperako kwambiri a protein-fatty kapena w proteni ya proteni.

Zomwe zapezedwa pakhungu pamayeso osambitsa mikono zimawonetsa kusanja komweko monga mu Mayeso osinthidwa a Duhring Chamber Test pomwe machitidwe osakanikirana a alkyl ether sulfate ndi alkyl polyglycosides kapena amphoteric co-surfactants amafufuzidwa. Komabe, kuyesa kwa flex flex wash kumathandizira kusiyanitsa kwabwinoko. Mapangidwe a erythema ndi squamation akhoza kuchepetsedwa ndi 20-30 D/o ngati mozungulira 25 °10 wa SLES m'malo ndi alkyl polyglycoside yomwe imasonyeza kuchepetsa pafupifupi 60%. Pakumanga mwadongosolo kapangidwe kake, zabwino kwambiri zitha kukwaniritsidwa mwa kuwonjezera zotumphukira zama protein kapena amphoteric.